| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| guaB | pyrF | stu2016 | stu0967 | Inosine monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | orotidine-5-Phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.760 |
| guaB | stu0979 | stu2016 | stu0979 | Inosine monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 5'-nucleotidase, putative; Belongs to the 5'-nucleotidase family. | 0.918 |
| guaB | tmk | stu2016 | stu0489 | Inosine monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.751 |
| pyrF | guaB | stu0967 | stu2016 | orotidine-5-Phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | Inosine monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.760 |
| pyrF | stu0979 | stu0967 | stu0979 | orotidine-5-Phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 5'-nucleotidase, putative; Belongs to the 5'-nucleotidase family. | 0.909 |
| pyrF | stu1307 | stu0967 | stu1307 | orotidine-5-Phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | Hydrolase, haloacid dehalogenase-like family. | 0.902 |
| pyrF | udk | stu0967 | stu1260 | orotidine-5-Phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | Uridine kinase. | 0.916 |
| stu0139 | stu0140 | stu0139 | stu0140 | Cyclo-nucleotide phosphodiesterase, truncated; Truncated. | Cyclo-nucleotide phosphodiesterase, truncated; Truncated. | 0.990 |
| stu0139 | stu0141 | stu0139 | stu0141 | Cyclo-nucleotide phosphodiesterase, truncated; Truncated. | Cyclo-nucleotide phosphodiesterase, truncated; Truncated. | 0.990 |
| stu0139 | stu0142 | stu0139 | stu0142 | Cyclo-nucleotide phosphodiesterase, truncated; Truncated. | Cyclo-nucleotide phosphodiesterase, truncated; Truncated. | 0.989 |
| stu0139 | stu0979 | stu0139 | stu0979 | Cyclo-nucleotide phosphodiesterase, truncated; Truncated. | 5'-nucleotidase, putative; Belongs to the 5'-nucleotidase family. | 0.911 |
| stu0139 | stu1307 | stu0139 | stu1307 | Cyclo-nucleotide phosphodiesterase, truncated; Truncated. | Hydrolase, haloacid dehalogenase-like family. | 0.915 |
| stu0139 | udk | stu0139 | stu1260 | Cyclo-nucleotide phosphodiesterase, truncated; Truncated. | Uridine kinase. | 0.904 |
| stu0140 | stu0139 | stu0140 | stu0139 | Cyclo-nucleotide phosphodiesterase, truncated; Truncated. | Cyclo-nucleotide phosphodiesterase, truncated; Truncated. | 0.990 |
| stu0140 | stu0141 | stu0140 | stu0141 | Cyclo-nucleotide phosphodiesterase, truncated; Truncated. | Cyclo-nucleotide phosphodiesterase, truncated; Truncated. | 0.994 |
| stu0140 | stu0142 | stu0140 | stu0142 | Cyclo-nucleotide phosphodiesterase, truncated; Truncated. | Cyclo-nucleotide phosphodiesterase, truncated; Truncated. | 0.993 |
| stu0140 | stu0979 | stu0140 | stu0979 | Cyclo-nucleotide phosphodiesterase, truncated; Truncated. | 5'-nucleotidase, putative; Belongs to the 5'-nucleotidase family. | 0.926 |
| stu0140 | stu1307 | stu0140 | stu1307 | Cyclo-nucleotide phosphodiesterase, truncated; Truncated. | Hydrolase, haloacid dehalogenase-like family. | 0.902 |
| stu0140 | udk | stu0140 | stu1260 | Cyclo-nucleotide phosphodiesterase, truncated; Truncated. | Uridine kinase. | 0.904 |
| stu0141 | stu0139 | stu0141 | stu0139 | Cyclo-nucleotide phosphodiesterase, truncated; Truncated. | Cyclo-nucleotide phosphodiesterase, truncated; Truncated. | 0.990 |