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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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co-expression
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[Homology]
Score
pepNLysyl-aminopeptidase, aminopeptidase N. (846 aa)    
Predicted Functional Partners:
pepXP
X-prolyl dipeptidyl peptidase; Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline; Belongs to the peptidase S15 family.
 
   
 0.969
pepP
Aminopeptidase P; XAA-pro aminopeptidase; Belongs to the peptidase M24B family.
  
 
 0.947
pepO
Endopeptidase O.
 
   
 0.942
pepQ
Dipeptidase; Belongs to the peptidase M24B family.
  
 
 0.927
pepV
Dipeptidase.
  
 
 0.925
pepM
Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
   
 
 0.922
pepT
Tripeptidase; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
      
 0.917
gshAB
Conserved hypothetical protein; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine.
   
 
 0.911
dtpT
Di- or tripeptide:H+ symporter; Belongs to the PTR2/POT transporter (TC 2.A.17) family.
  
 
 0.904
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.902
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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