Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
acoCAcetoin/pyruvate dehydrogenase complex, E2 component, dihydrolipoamide succinyltransferase. (462 aa)    
Predicted Functional Partners:
acoB
Acetoin dehydrogenase complex, E1 component, beta subunit.
 
 0.999
acoA
Acetoin dehydrogenase complex, E1 component, alpha subunit.
 
 0.999
acoL
Acetoin/pyruvate dehydrogenase complex, E3 component, dihydrolipoamide dehydrogenase.
 
0.995
gltA
Citrate synthase; Belongs to the citrate synthase family.
  
 0.974
lplA
Lipoate-protein ligase.
 
 0.953
pta
Phosphotransacetylase.
  
 
 0.928
stu1882
Alcohol-acetaldehyde dehydrogenase, truncated; Truncated.
  
 
 0.924
pfl
Pyruvate formate-lyase.
   
 
 0.919
accB
Biotoin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 
 0.914
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
    
 0.914
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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