Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
acoBAcetoin dehydrogenase complex, E1 component, beta subunit. (337 aa)    
Predicted Functional Partners:
acoL
Acetoin/pyruvate dehydrogenase complex, E3 component, dihydrolipoamide dehydrogenase.
 
 0.999
acoC
Acetoin/pyruvate dehydrogenase complex, E2 component, dihydrolipoamide succinyltransferase.
 
 0.999
acoA
Acetoin dehydrogenase complex, E1 component, alpha subunit.
 0.999
hdhL
L-2-hydroxyisocaproate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.954
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 0.954
pfl
Pyruvate formate-lyase.
   
 
 0.942
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.920
ilvN
Acetolactate synthase, small subunit.
   
 
 0.864
gapN
NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.854
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.852
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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