Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
eps9Exopolysaccharide biosynthesis protein. (185 aa)    
Predicted Functional Partners:
eps10
Exopolysaccharide biosynthesis protein, glycosyltransferase.
     
 0.916
birA
biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
  
 0.665
eps11
Exopolysaccharide biosynthesis protein, glycosyltransferase.
       0.587
pps
Non-ribosomal peptide synthetase.
 
  
 0.478
eps12
Exopolysaccharide biosynthesis protein, predicted membrane protein.
  
  
 0.459
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.431
stu1106
Exopolysaccharide biosynthesis protein, truncated; Truncated.
  
  
 0.404
stu1107
Exopolysaccharide biosynthesis protein, truncated; Truncated.
  
  
 0.404
epsE
Exopolysaccharide biosynthesis protein, glycosyl-1-phosphate transferase.
  
  
 0.404
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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