STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xylH4-oxalocrotonate tautomerase. (61 aa)    
Predicted Functional Partners:
stu1365
Conserved hypothetical protein, truncated; Truncated.
    
 0.913
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.607
nox
NADH oxidase (H2O-forming).
     
 0.585
pepV
Dipeptidase.
 
     0.577
stu0727
Conserved hypothetical protein.
  
     0.524
stu1278
Truncated.
 
     0.485
stu0595
Unknown protein.
 
     0.456
stu1126
Conserved hypothetical protein.
       0.455
stu2004
Conserved hypothetical, predicted membrane protein (TMS10).
  
     0.445
stu1883
Alcohol-acetaldehyde dehydrogenase, truncated; Truncated.
 
   
 0.425
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.