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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfk6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (355 aa)    
Predicted Functional Partners:
fba
Fructose-bisphosphate aldolase.
 
 
 0.984
pgi
Glucose-6-phosphate isomerase.
  
 0.979
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
 
 
 0.975
fruB
Fructose-1-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
  
  
 0.966
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
   
  
 0.954
eno
2-phosphoglycerate dehydratase, enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
  
 0.938
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.933
scrK
Fructokinase.
    
 0.912
stu1358
Mannose-6-phosphate isomerase, truncated; Truncated.
    
 0.909
stu1359
Mannose-6-phosphate isomerase, truncated; Truncated.
    
 0.909
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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