| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| hstH | pyrDa | stu1209 | stu1207 | Histone-like DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Dihydroorotate dehydrogenase A; Catalyzes the conversion of dihydroorotate to orotate. | 0.783 |
| hstH | pyrDb | stu1209 | stu0955 | Histone-like DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Dihydroorotate dehydrogenase B; Catalyzes the conversion of dihydroorotate to orotate. | 0.783 |
| hstH | recX | stu1209 | stu0375 | Histone-like DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Regulatory protein recX; Modulates RecA activity; Belongs to the RecX family. | 0.720 |
| hstH | rplS | stu1209 | stu1179 | Histone-like DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.721 |
| hstH | rpsT | stu1209 | stu0798 | Histone-like DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. | 0.645 |
| hstH | stu1210 | stu1209 | stu1210 | Histone-like DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Conserved hypothetical protein. | 0.696 |
| hstH | stu1211 | stu1209 | stu1211 | Histone-like DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Conserved hypothetical protein. | 0.703 |
| hstH | stu1212 | stu1209 | stu1212 | Histone-like DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Conserved hypothetical protein, degV family. | 0.669 |
| hstH | topA | stu1209 | stu0897 | Histone-like DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.753 |
| hstH | xseB | stu1209 | stu1217 | Histone-like DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.662 |
| pyrDa | hstH | stu1207 | stu1209 | Dihydroorotate dehydrogenase A; Catalyzes the conversion of dihydroorotate to orotate. | Histone-like DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 0.783 |
| pyrDa | pyrDb | stu1207 | stu0955 | Dihydroorotate dehydrogenase A; Catalyzes the conversion of dihydroorotate to orotate. | Dihydroorotate dehydrogenase B; Catalyzes the conversion of dihydroorotate to orotate. | 0.917 |
| pyrDb | hstH | stu0955 | stu1209 | Dihydroorotate dehydrogenase B; Catalyzes the conversion of dihydroorotate to orotate. | Histone-like DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 0.783 |
| pyrDb | pyrDa | stu0955 | stu1207 | Dihydroorotate dehydrogenase B; Catalyzes the conversion of dihydroorotate to orotate. | Dihydroorotate dehydrogenase A; Catalyzes the conversion of dihydroorotate to orotate. | 0.917 |
| recX | hstH | stu0375 | stu1209 | Regulatory protein recX; Modulates RecA activity; Belongs to the RecX family. | Histone-like DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 0.720 |
| recX | topA | stu0375 | stu0897 | Regulatory protein recX; Modulates RecA activity; Belongs to the RecX family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.685 |
| rplS | hstH | stu1179 | stu1209 | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | Histone-like DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 0.721 |
| rplS | rpsT | stu1179 | stu0798 | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. | 0.980 |
| rplS | topA | stu1179 | stu0897 | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.471 |
| rpsT | hstH | stu0798 | stu1209 | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. | Histone-like DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 0.645 |
