Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
stu1235acyl-ACP thioesterase, putative. (247 aa)    
Predicted Functional Partners:
stu1233
Conserved hypothetical, predicted membrane protein (TMS4).
 
     0.876
hemN
Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
       0.848
stu1234
N-acetyl-glucosamine catabolism protein, putative.
       0.847
hisK
Histidinol-phosphatase, putative; Belongs to the PHP hydrolase family. HisK subfamily.
       0.773
stu1462
Conserved hypothetical protein.
  
     0.588
stu1231
Unknown protein.
       0.532
stu0316
Conserved hypothetical protein.
  
     0.490
stu0492
Conserved hypothetical protein; Involved in initiation control of chromosome replication. Belongs to the YabA family.
 
     0.441
stu1237
Unknown protein.
       0.416
stu0636
Conserved hypothetical, predicted membrane protein (TMS5).
  
     0.409
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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