| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| gyrA | ldh | stu1279 | stu1280 | DNA gyrase A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. | 0.700 |
| gyrA | stu1276 | stu1279 | stu1276 | DNA gyrase A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Conserved hypothetical protein. | 0.678 |
| gyrA | stu1277 | stu1279 | stu1277 | DNA gyrase A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Truncated. | 0.772 |
| gyrA | stu1278 | stu1279 | stu1278 | DNA gyrase A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Truncated. | 0.781 |
| ldh | gyrA | stu1280 | stu1279 | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. | DNA gyrase A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.700 |
| ldh | stu1276 | stu1280 | stu1276 | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. | Conserved hypothetical protein. | 0.488 |
| ldh | stu1277 | stu1280 | stu1277 | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. | Truncated. | 0.454 |
| ldh | stu1278 | stu1280 | stu1278 | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. | Truncated. | 0.461 |
| msrA1 | stu1277 | stu1343 | stu1277 | Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Truncated. | 0.785 |
| msrA1 | stu1278 | stu1343 | stu1278 | Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Truncated. | 0.785 |
| mur3 | rpoE | stu0117 | stu0133 | Peptidoglycan hydrolase. | DNA-directed RNA polymerase delta subunit; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. | 0.500 |
| mur3 | stu1277 | stu0117 | stu1277 | Peptidoglycan hydrolase. | Truncated. | 0.457 |
| mur3 | stu1750 | stu0117 | stu1750 | Peptidoglycan hydrolase. | Conserved hypothetical, predicted membrane protein (TMS4). | 0.530 |
| phoH | stu1277 | stu0447 | stu1277 | Phosphate starvation-induced protein. | Truncated. | 0.792 |
| phoH | stu1278 | stu0447 | stu1278 | Phosphate starvation-induced protein. | Truncated. | 0.792 |
| recJ | stu1277 | stu1224 | stu1277 | Single strand DNA-specific exonuclease. | Truncated. | 0.474 |
| recJ | stu1278 | stu1224 | stu1278 | Single strand DNA-specific exonuclease. | Truncated. | 0.474 |
| rpoE | mur3 | stu0133 | stu0117 | DNA-directed RNA polymerase delta subunit; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. | Peptidoglycan hydrolase. | 0.500 |
| rpoE | stu1277 | stu0133 | stu1277 | DNA-directed RNA polymerase delta subunit; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. | Truncated. | 0.669 |
| rpoE | stu1278 | stu0133 | stu1278 | DNA-directed RNA polymerase delta subunit; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. | Truncated. | 0.597 |