STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gshABConserved hypothetical protein; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine. (754 aa)    
Predicted Functional Partners:
gnlA
Glutamine synthetase.
  
 
 0.957
metB2
Cystathionine beta-lyase.
    
 0.926
bcaT
Branched chain amino acid aminotransferase.
  
 
 0.911
pepN
Lysyl-aminopeptidase, aminopeptidase N.
     
 0.909
gor
Glutathione reductase (GR).
  
   
 0.903
gloA
Glyoxalase I/lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
  
  
 0.851
cysM1
Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.850
cysM2
Cysteine synthase.
    
 0.850
gdhA
NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.822
stu0353
Aminotransferase (class II).
     
  0.800
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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