STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rr08Response regulator (homolog to RR03 Spn). (214 aa)    
Predicted Functional Partners:
hk08
Sensor histidine kinase (homolog to HK03 Spn).
 
 0.999
stu1422
Conserved hypothetical, predicted membrane protein (TMS3).
 
  
 0.941
hk06
Sensor histidine kinase (homolog to HK11 Spn).
 
 
 0.917
hk01
Sensor histidine kinase (homolog to csrS/covS Spy).
 
 
 0.759
stu1380
Response regulator (homolog to RR08 Spn) uncoupled, truncated; Truncated.
  
 
 0.583
stu1327
ABC transporter membrane-spanning protein.
 
  
 0.537
hk07
Sensor histidine kinase (homolog to HK01Spn & Sth).
 
 
 0.535
pknB
Protein kinase.
 
   
 0.481
stu1558
Hypothetical protein.
 
     0.480
stu0277
Urease cluster protein, truncated; Truncated.
  
 
 0.460
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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