STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hk08Sensor histidine kinase (homolog to HK03 Spn). (336 aa)    
Predicted Functional Partners:
rr08
Response regulator (homolog to RR03 Spn).
 
 0.999
stu1422
Conserved hypothetical, predicted membrane protein (TMS3).
 
  
 0.969
rr06
Response regulator (homolog to RR11 Spn).
 
 
 0.918
hk06
Sensor histidine kinase (homolog to HK11 Spn).
  
     0.772
stu1380
Response regulator (homolog to RR08 Spn) uncoupled, truncated; Truncated.
 
 
 0.631
hk01
Sensor histidine kinase (homolog to csrS/covS Spy).
  
 
 0.605
rr01
Response regulator (homolog to csrR/covR Spy).
  
 
 0.579
pbp1B
Penicillin-binding protein 1B.
  
  
 0.570
stu0665
Conserved hypothetical protein.
  
  
 0.549
stu1558
Hypothetical protein.
 
     0.542
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.