Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
stu1435Transcriptional regulator, GntR family, putative. (125 aa)    
Predicted Functional Partners:
stu1437
ABC transporter membrane-spanning protein.
 
  
 0.990
stu1436
ABC transporter ATP binding protein.
 
  
 0.982
nadR
Transcriptional regulator.
   
    0.845
stu0546
ABC transporter ATP binding protein.
  
  
 0.563
stu1328
ABC transporter ATP binding protein.
  
  
 0.563
stu1434
Conserved hypothetical protein, Cof family.
       0.522
ftsY
Signal recognition particle receptor (docking protein); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
       0.509
stu1433
Conserved hypothetical protein, Cof family.
       0.505
stu1858
Conserved hypothetical protein.
   
    0.439
pfk
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
       0.431
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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