STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rexConserved hypothetical protein, putative DNA-binding protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. (231 aa)    
Predicted Functional Partners:
stu1464
Glutamine amidotransferase (class I), putative.
       0.800
comGC
Late competence protein, exogenous DNA-binding protein.
  
   
 0.795
rnpA
Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
   
    0.677
prsA2
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
       0.573
nifS3
Aminotransferase (class V), putative.
       0.573
stu1462
Conserved hypothetical protein.
       0.573
stu1882
Alcohol-acetaldehyde dehydrogenase, truncated; Truncated.
  
  
 0.507
stu1883
Alcohol-acetaldehyde dehydrogenase, truncated; Truncated.
  
  
 0.507
rpsP
30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
   
    0.501
stu0423
Conserved hypothetical protein, degV family, truncated; Truncated.
  
   
 0.452
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.