Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
radCDNA repair protein; Belongs to the UPF0758 family. (228 aa)    
Predicted Functional Partners:
cinA
Competence/damage inducible protein; Belongs to the CinA family.
     
 0.863
comFA
Late competence protein required for DNA uptake.
      
 0.838
radA
DNA repair protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
 
   
 0.834
rgpF
Polysaccharide biosynthesis protein.
     
 0.806
comEC
Late competence protein required for DNA uptake.
  
  
 0.806
rgpA
Polysaccharide biosynthesis protein/putative rhamnosyl transferase.
     
 0.776
mreC
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
 
  
 0.756
rgpB
Polysaccharide biosynthesis protein/putative rhamnosyl transferase.
     
 0.753
rgpE
Polysaccharide biosynthesis protein/putative glycosyltransferase.
     
 0.736
rgpC
Polysaccharide ABC exporter membrane-spanning protein.
     
 0.735
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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