Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
stu1545Conserved hypothetical, predicted membrane protein (TMS11). (614 aa)    
Predicted Functional Partners:
folC2
Folylpolyglutamate synthase / dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family.
  
  
 0.600
folE
GTP cyclohydrolase I.
     
 0.519
amyL
Alpha-amylase.
   
 0.489
stu1886
Trehalose-6-phosphate hydrolase, truncated; Truncated.
   
 0.489
stu1887
Trehalose-6-phosphate hydrolase, truncated; Truncated.
   
 0.489
folP
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
       0.451
dtpT
Di- or tripeptide:H+ symporter; Belongs to the PTR2/POT transporter (TC 2.A.17) family.
  
 
 
 0.411
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
Server load: low (18%) [HD]