Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
comECLate competence protein required for DNA uptake. (746 aa)    
Predicted Functional Partners:
comEA
Late competence protein required for DNA binding and uptake.
 
  
 0.994
comFC
Late competence protein.
 
  
 0.969
dprA
DNA processing protein, Smf family.
 
  
 0.955
comFA
Late competence protein required for DNA uptake.
   
  
 0.943
comGA
Late competence protein, ABC transporter subunit.
 
  
 0.938
cinA
Competence/damage inducible protein; Belongs to the CinA family.
     
 0.931
comGB
Late competence protein, ABC transporter subunit.
 
  
 0.895
pilD
Prepilin peptidase type IV.
 
  
 0.868
recA
Recombination protein A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
  
 0.855
comEB
Late competence protein required for DNA binding and uptake.
  
  
 0.842
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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