Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
stu1571Conserved hypothetical, predicted membrane protein (TMS4). (191 aa)    
Predicted Functional Partners:
ecfT
ABC transporter membrane-spanning protein; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. Expression of the complex plus RibU in de- energized E.coli allows riboflavin uptake.
  
  
 0.783
ecfA1
ABC transporter ATP binding protein; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity). Expression of the complex plus RibU in de-energized E.coli allows riboflavin uptake.
  
   
 0.743
ribU
Conserved hypothetical, predicted membrane protein (TMS5); Substrate-binding (S) component of an energy-coupling factor (ECF) ABC-transporter complex. Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins (Probable). Expression of the compl [...]
  
   
 0.739
ecfA2
ABC transporter ATP binding protein; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity). Expression of the complex plus RibU in de-energized E.coli allows riboflavin uptake.
  
   
 0.737
stu1763
Conserved hypothetical, predicted membrane protein (TMS4).
  
     0.700
pbp1B
Penicillin-binding protein 1B.
  
     0.524
stu1422
Conserved hypothetical, predicted membrane protein (TMS3).
  
     0.519
stu0717
Conserved hypothetical protein.
 
     0.507
stu0124
Conserved hypothetical, predicted membrane protein (TMS3).
      
 0.501
thiD
Phosphomethylpyrimidine kinase.
  
  
 0.488
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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