STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
copACu2+-Cu+-Ag+-P-type ATPase. (742 aa)    
Predicted Functional Partners:
copZ
Putative copper chaperone - Cu2+-Cu+-Ag+-P-type ATPase.
  
 
 0.935
copY
Negative transcriptional regulator - copper transport operon.
  
  
 0.827
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
 0.523
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
     
 0.512
trpC
Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.
       0.503
trpF
N-(5'-phosphoribosyl)-anthranilate isomerase; Belongs to the TrpF family.
  
    0.493
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
       0.482
adcA
Zinc (Zn2+) ABC uptake transporter substrate binding protein; Belongs to the bacterial solute-binding protein 9 family.
     
 0.450
trpG
Anthranilate synthase component II.
  
  
 0.442
stu0351
Ca2+, Mn2+-P-type ATPase, truncated; Truncated.
 
 0.408
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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