STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pflPyruvate formate-lyase. (769 aa)    
Predicted Functional Partners:
pflA
Pyruvate-formate lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.
  
 0.989
pta
Phosphotransacetylase.
  
 
 0.968
stu1882
Alcohol-acetaldehyde dehydrogenase, truncated; Truncated.
 
 
 0.963
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.943
hdhL
L-2-hydroxyisocaproate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 
 0.942
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 
 0.942
acoL
Acetoin/pyruvate dehydrogenase complex, E3 component, dihydrolipoamide dehydrogenase.
   
 
 0.937
stu1884
Alcohol-acetaldehyde dehydrogenase, truncated; Truncated.
 
 
 0.933
acoB
Acetoin dehydrogenase complex, E1 component, beta subunit.
   
 
 0.932
ilvB
Acetolactate synthase, large subunit.
     
 0.931
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.