Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
blpUPore-forming peptide, putative bacteriocin. (76 aa)    
Predicted Functional Partners:
blpX
Bacteriocin self-immunity protein, putative.
      
 0.741
blpC
Signal peptide, putative.
      
 0.720
blpA
Bacteriocin ABC exporter (Pep2E family), ATP binding/membrane-spanning protein.
      
 0.666
rmlB
dTDP-glucose-4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
      
 0.629
rmlD
dTDP-4-keto-L-rhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.
      
 0.629
stu1602
Conserved hypothetical protein.
      
 0.627
rr09
Response regulator (homolog to BlpR Spn).
       0.454
hk09
Sensor histidine kinase (homolog to BlpH Spn).
       0.454
stu1684
Hypothetical membrane protein.
       0.435
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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