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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
blpCSignal peptide, putative. (53 aa)    
Predicted Functional Partners:
hk09
Sensor histidine kinase (homolog to BlpH Spn).
     
  0.900
stu1689
Bacteriocin ABC exporter accessory protein, truncated; Truncated.
       0.746
plcR
Transcriptional regulator.
      
 0.729
blpU
Pore-forming peptide, putative bacteriocin.
      
 0.726
htrA
Exported serine protease.
      
 0.721
blpA
Bacteriocin ABC exporter (Pep2E family), ATP binding/membrane-spanning protein.
     
 0.643
stu1690
Bacteriocin ABC exporter accessory protein, truncated; Truncated.
       0.481
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.