comEB protein (Streptococcus thermophilus) - STRING interaction network

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Score

comEB

Late competence protein required for DNA binding and uptake. (156 aa)

Predicted Functional Partners:

pepP

0.947

dut

0.930

thyA

0.923

tdk

0.920

tmk

0.914

stu1307

0.909

stu0979

0.904

cmk

0.903

comEC

0.842

comEA

0.756

Your Current Organism:

Streptococcus thermophilus

NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cmk	comEB	stu1135	stu1741	Cytidylate kinase.	Late competence protein required for DNA binding and uptake.	0.903
cmk	stu0979	stu1135	stu0979	Cytidylate kinase.	5'-nucleotidase, putative; Belongs to the 5'-nucleotidase family.	0.900
cmk	stu1307	stu1135	stu1307	Cytidylate kinase.	Hydrolase, haloacid dehalogenase-like family.	0.900
comEA	comEB	stu1562	stu1741	Late competence protein required for DNA binding and uptake.	Late competence protein required for DNA binding and uptake.	0.756
comEA	comEC	stu1562	stu1561	Late competence protein required for DNA binding and uptake.	Late competence protein required for DNA uptake.	0.994
comEB	cmk	stu1741	stu1135	Late competence protein required for DNA binding and uptake.	Cytidylate kinase.	0.903
comEB	comEA	stu1741	stu1562	Late competence protein required for DNA binding and uptake.	Late competence protein required for DNA binding and uptake.	0.756
comEB	comEC	stu1741	stu1561	Late competence protein required for DNA binding and uptake.	Late competence protein required for DNA uptake.	0.842
comEB	dut	stu1741	stu1824	Late competence protein required for DNA binding and uptake.	Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase); This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	0.930
comEB	pepP	stu1741	stu1742	Late competence protein required for DNA binding and uptake.	Aminopeptidase P; XAA-pro aminopeptidase; Belongs to the peptidase M24B family.	0.947
comEB	stu0979	stu1741	stu0979	Late competence protein required for DNA binding and uptake.	5'-nucleotidase, putative; Belongs to the 5'-nucleotidase family.	0.904
comEB	stu1307	stu1741	stu1307	Late competence protein required for DNA binding and uptake.	Hydrolase, haloacid dehalogenase-like family.	0.909
comEB	tdk	stu1741	stu0751	Late competence protein required for DNA binding and uptake.	Thymidine kinase.	0.920
comEB	thyA	stu1741	stu0578	Late competence protein required for DNA binding and uptake.	Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.	0.923
comEB	tmk	stu1741	stu0489	Late competence protein required for DNA binding and uptake.	Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.	0.914
comEC	comEA	stu1561	stu1562	Late competence protein required for DNA uptake.	Late competence protein required for DNA binding and uptake.	0.994
comEC	comEB	stu1561	stu1741	Late competence protein required for DNA uptake.	Late competence protein required for DNA binding and uptake.	0.842
dut	comEB	stu1824	stu1741	Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase); This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	Late competence protein required for DNA binding and uptake.	0.930
dut	stu0979	stu1824	stu0979	Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase); This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	5'-nucleotidase, putative; Belongs to the 5'-nucleotidase family.	0.900
dut	stu1307	stu1824	stu1307	Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase); This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	Hydrolase, haloacid dehalogenase-like family.	0.902

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