Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
stu1763Conserved hypothetical, predicted membrane protein (TMS4). (180 aa)    
Predicted Functional Partners:
purL
Phosphoribosylformylglycinamidine synthase II (FGAM synthetase).
  
  
 0.966
purF
Amidophosphoribosyltransferase (PRPP amidotransferase); Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
  
 0.900
stu1764
Conserved hypothetical protein.
       0.860
pbp1B
Penicillin-binding protein 1B.
 
     0.774
stu1422
Conserved hypothetical, predicted membrane protein (TMS3).
  
     0.747
rnhB
Ribonuclease HIII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. RnhC subfamily.
 
   
 0.739
stu1571
Conserved hypothetical, predicted membrane protein (TMS4).
  
     0.700
purM
Phosphoribosylformylglycinamide cyclo-ligase (AIR synthetase).
   
    0.693
stu1458
Conserved hypothetical protein.
  
     0.674
purC
Phosphoribosylaminoimidazole - succinocarboxamide synthase (SAICAR synthetase).
  
    0.661
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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