Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gnlAGlutamine synthetase. (456 aa)    
Predicted Functional Partners:
gdhA
NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.992
gnlR
Transcriptional regulator, repressor of the glutamine synthetase, MerR family.
 
 
 0.992
glmS
Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
 
 
 0.958
gshAB
Conserved hypothetical protein; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine.
    
 0.954
carB
Carbamoyl phosphate synthetase, large chain.
  
 0.945
carA
Carbamoyl phosphate synthetase, small chain; Belongs to the CarA family.
  
 
 0.922
purF
Amidophosphoribosyltransferase (PRPP amidotransferase); Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
 0.915
acoL
Acetoin/pyruvate dehydrogenase complex, E3 component, dihydrolipoamide dehydrogenase.
  
 
 0.882
glr
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
    
 0.875
alr
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
     
 0.861
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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