| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| birA | dnaJ | stu1173 | stu0121 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Heat shock protein, chaperonin; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...] | 0.458 |
| birA | gnlA | stu1173 | stu1776 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Glutamine synthetase. | 0.464 |
| birA | gnlR | stu1173 | stu1777 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Transcriptional regulator, repressor of the glutamine synthetase, MerR family. | 0.432 |
| birA | rpoA | stu1173 | stu1908 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | DNA-directed RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.484 |
| dnaJ | birA | stu0121 | stu1173 | Heat shock protein, chaperonin; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...] | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.458 |
| dnaJ | gnlR | stu0121 | stu1777 | Heat shock protein, chaperonin; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...] | Transcriptional regulator, repressor of the glutamine synthetase, MerR family. | 0.791 |
| dnaJ | rpoD | stu0121 | stu1488 | Heat shock protein, chaperonin; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...] | DNA directed RNA polymerase sigma 42 protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.627 |
| gnlA | birA | stu1776 | stu1173 | Glutamine synthetase. | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.464 |
| gnlA | gnlR | stu1776 | stu1777 | Glutamine synthetase. | Transcriptional regulator, repressor of the glutamine synthetase, MerR family. | 0.964 |
| gnlA | stu1778 | stu1776 | stu1778 | Glutamine synthetase. | Conserved hypothetical, predicted membrane protein (TMS5). | 0.498 |
| gnlR | birA | stu1777 | stu1173 | Transcriptional regulator, repressor of the glutamine synthetase, MerR family. | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.432 |
| gnlR | dnaJ | stu1777 | stu0121 | Transcriptional regulator, repressor of the glutamine synthetase, MerR family. | Heat shock protein, chaperonin; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...] | 0.791 |
| gnlR | gnlA | stu1777 | stu1776 | Transcriptional regulator, repressor of the glutamine synthetase, MerR family. | Glutamine synthetase. | 0.964 |
| gnlR | rpoA | stu1777 | stu1908 | Transcriptional regulator, repressor of the glutamine synthetase, MerR family. | DNA-directed RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.596 |
| gnlR | rpoB | stu1777 | stu1868 | Transcriptional regulator, repressor of the glutamine synthetase, MerR family. | DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.643 |
| gnlR | rpoC | stu1777 | stu1867 | Transcriptional regulator, repressor of the glutamine synthetase, MerR family. | DNA-directed RNA polymerase B prime subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.566 |
| gnlR | rpoD | stu1777 | stu1488 | Transcriptional regulator, repressor of the glutamine synthetase, MerR family. | DNA directed RNA polymerase sigma 42 protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.640 |
| gnlR | rpoZ | stu1777 | stu1430 | Transcriptional regulator, repressor of the glutamine synthetase, MerR family. | DNA-directed RNA polymerase, omega subunit, putative; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.578 |
| gnlR | stu1773 | stu1777 | stu1773 | Transcriptional regulator, repressor of the glutamine synthetase, MerR family. | Conserved hypothetical protein; Belongs to the UPF0356 family. | 0.527 |
| gnlR | stu1778 | stu1777 | stu1778 | Transcriptional regulator, repressor of the glutamine synthetase, MerR family. | Conserved hypothetical, predicted membrane protein (TMS5). | 0.528 |