Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
pepOEndopeptidase O. (631 aa)    
Predicted Functional Partners:
pepN
Lysyl-aminopeptidase, aminopeptidase N.
 
   
 0.942
pepXP
X-prolyl dipeptidyl peptidase; Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline; Belongs to the peptidase S15 family.
     
 0.934
pepP
Aminopeptidase P; XAA-pro aminopeptidase; Belongs to the peptidase M24B family.
   
  
 0.930
pepT
Tripeptidase; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
   
  
 0.918
pepV
Dipeptidase.
      
 0.908
pepQ
Dipeptidase; Belongs to the peptidase M24B family.
   
  
 0.886
pepM
Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
 
  
 0.824
pepB
Oligopeptidase.
      
 0.817
pepC
Cysteine aminopeptidase C; Belongs to the peptidase C1 family.
  
   
 0.805
pepS
Aminopeptidase PepS.
      
 0.779
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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