Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
int-3Integrase/recombinase, phage associated; Belongs to the 'phage' integrase family. (379 aa)    
Predicted Functional Partners:
stu1954
Conserved hypothetical protein.
       0.837
rip
Replication initiator protein.
       0.811
int-2
Integrase/recombinase plasmid associated, putative.
     
 0.798
ssbA
Single strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
     
 0.544
comFC
Late competence protein.
   
    0.490
ssbB
Single strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
     
 0.453
tyrA
Prephenate dehydrogenase.
  
    0.446
whiA
Conserved hypothetical protein; Involved in cell division and chromosome segregation.
   
    0.426
rpsU
30S ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.
   
 
 0.412
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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