node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CF0406 | CF0409 | gene:10544225 | gene:10544228 | Conserved hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | Conserved hypothetical protein. | 0.670 |
CF0406 | kdtA2 | gene:10544225 | CF0408 | Conserved hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.845 |
CF0406 | oppA4 | gene:10544225 | CF0405 | Conserved hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | ABC transporter/periplasmic oligopeptide binding lipoprotein component. | 0.415 |
CF0406 | pyrG | gene:10544225 | CF0407 | Conserved hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.845 |
CF0409 | CF0406 | gene:10544228 | gene:10544225 | Conserved hypothetical protein. | Conserved hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | 0.670 |
CF0409 | kdtA2 | gene:10544228 | CF0408 | Conserved hypothetical protein. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.670 |
CF0409 | pyrG | gene:10544228 | CF0407 | Conserved hypothetical protein. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.670 |
aroG2 | kdtA1 | CF0985 | CF0392 | 2-dehydro-3-deoxyphosphooctonate aldolase; EC 4.1.2.16; Belongs to the KdsA family. | 3-deoxy-manno-octulosonate cytidylyltransferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.621 |
aroG2 | kdtA2 | CF0985 | CF0408 | 2-dehydro-3-deoxyphosphooctonate aldolase; EC 4.1.2.16; Belongs to the KdsA family. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.829 |
aroG2 | kpsF | CF0985 | CF0788 | 2-dehydro-3-deoxyphosphooctonate aldolase; EC 4.1.2.16; Belongs to the KdsA family. | Sugar-phosphate isomerase-like protein; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.991 |
aroG2 | lpxB | CF0985 | CF0221 | 2-dehydro-3-deoxyphosphooctonate aldolase; EC 4.1.2.16; Belongs to the KdsA family. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.832 |
aroG2 | ribA | CF0985 | CF0119 | 2-dehydro-3-deoxyphosphooctonate aldolase; EC 4.1.2.16; Belongs to the KdsA family. | Riboflavin biosynthesis protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.406 |
aroG2 | ycaH | CF0985 | CF0791 | 2-dehydro-3-deoxyphosphooctonate aldolase; EC 4.1.2.16; Belongs to the KdsA family. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.675 |
kdtA1 | aroG2 | CF0392 | CF0985 | 3-deoxy-manno-octulosonate cytidylyltransferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 2-dehydro-3-deoxyphosphooctonate aldolase; EC 4.1.2.16; Belongs to the KdsA family. | 0.621 |
kdtA1 | kdtA2 | CF0392 | CF0408 | 3-deoxy-manno-octulosonate cytidylyltransferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.977 |
kdtA1 | kpsF | CF0392 | CF0788 | 3-deoxy-manno-octulosonate cytidylyltransferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Sugar-phosphate isomerase-like protein; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.766 |
kdtA1 | lpxB | CF0392 | CF0221 | 3-deoxy-manno-octulosonate cytidylyltransferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.848 |
kdtA1 | ycaH | CF0392 | CF0791 | 3-deoxy-manno-octulosonate cytidylyltransferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.999 |
kdtA2 | CF0406 | CF0408 | gene:10544225 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | Conserved hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | 0.845 |
kdtA2 | CF0409 | CF0408 | gene:10544228 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | Conserved hypothetical protein. | 0.670 |