node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ZMO0405 | ZMO1069 | ZMO0405 | ZMO1069 | TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; Torsin; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; ATP-dependent Clp protease ATP-binding subunit clpA; KEGG: swi:Swit_0126 ATP-dependent Clp protease, ATP-binding subunit ClpA; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | PFAM: heat shock protein DnaJ domain protein; KEGG: swi:Swit_2948 heat shock protein DnaJ domain-containing protein. | 0.607 |
ZMO0405 | ZMO1545 | ZMO0405 | ZMO1545 | TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; Torsin; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; ATP-dependent Clp protease ATP-binding subunit clpA; KEGG: swi:Swit_0126 ATP-dependent Clp protease, ATP-binding subunit ClpA; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | PFAM: heat shock protein DnaJ domain protein; KEGG: swi:Swit_2332 heat shock protein DnaJ domain-containing protein. | 0.607 |
ZMO0405 | ZMO1690 | ZMO0405 | ZMO1690 | TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; Torsin; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; ATP-dependent Clp protease ATP-binding subunit clpA; KEGG: swi:Swit_0126 ATP-dependent Clp protease, ATP-binding subunit ClpA; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: swi:Swit_4767 heat shock protein DnaJ domain-containing protein. | 0.800 |
ZMO0405 | dnaJ | ZMO0405 | ZMO0661 | TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; Torsin; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; ATP-dependent Clp protease ATP-binding subunit clpA; KEGG: swi:Swit_0126 ATP-dependent Clp protease, ATP-binding subunit ClpA; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.755 |
ZMO0405 | dnaK | ZMO0405 | ZMO0660 | TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; Torsin; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; ATP-dependent Clp protease ATP-binding subunit clpA; KEGG: swi:Swit_0126 ATP-dependent Clp protease, ATP-binding subunit ClpA; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.975 |
ZMO0405 | groL | ZMO0405 | ZMO1929 | TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; Torsin; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; ATP-dependent Clp protease ATP-binding subunit clpA; KEGG: swi:Swit_0126 ATP-dependent Clp protease, ATP-binding subunit ClpA; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.580 |
ZMO0405 | groS | ZMO0405 | ZMO1928 | TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; Torsin; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; ATP-dependent Clp protease ATP-binding subunit clpA; KEGG: swi:Swit_0126 ATP-dependent Clp protease, ATP-binding subunit ClpA; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.586 |
ZMO0405 | grpE | ZMO0405 | ZMO0016 | TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; Torsin; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; ATP-dependent Clp protease ATP-binding subunit clpA; KEGG: swi:Swit_0126 ATP-dependent Clp protease, ATP-binding subunit ClpA; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.793 |
ZMO0405 | hrcA | ZMO0405 | ZMO0015 | TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; Torsin; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; ATP-dependent Clp protease ATP-binding subunit clpA; KEGG: swi:Swit_0126 ATP-dependent Clp protease, ATP-binding subunit ClpA; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.544 |
ZMO1069 | ZMO0405 | ZMO1069 | ZMO0405 | PFAM: heat shock protein DnaJ domain protein; KEGG: swi:Swit_2948 heat shock protein DnaJ domain-containing protein. | TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; Torsin; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; ATP-dependent Clp protease ATP-binding subunit clpA; KEGG: swi:Swit_0126 ATP-dependent Clp protease, ATP-binding subunit ClpA; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | 0.607 |
ZMO1069 | clpB | ZMO1069 | ZMO1424 | PFAM: heat shock protein DnaJ domain protein; KEGG: swi:Swit_2948 heat shock protein DnaJ domain-containing protein. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.607 |
ZMO1069 | dnaK | ZMO1069 | ZMO0660 | PFAM: heat shock protein DnaJ domain protein; KEGG: swi:Swit_2948 heat shock protein DnaJ domain-containing protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.957 |
ZMO1069 | groL | ZMO1069 | ZMO1929 | PFAM: heat shock protein DnaJ domain protein; KEGG: swi:Swit_2948 heat shock protein DnaJ domain-containing protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.577 |
ZMO1069 | groS | ZMO1069 | ZMO1928 | PFAM: heat shock protein DnaJ domain protein; KEGG: swi:Swit_2948 heat shock protein DnaJ domain-containing protein. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.536 |
ZMO1069 | grpE | ZMO1069 | ZMO0016 | PFAM: heat shock protein DnaJ domain protein; KEGG: swi:Swit_2948 heat shock protein DnaJ domain-containing protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.821 |
ZMO1069 | hrcA | ZMO1069 | ZMO0015 | PFAM: heat shock protein DnaJ domain protein; KEGG: swi:Swit_2948 heat shock protein DnaJ domain-containing protein. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.542 |
ZMO1545 | ZMO0405 | ZMO1545 | ZMO0405 | PFAM: heat shock protein DnaJ domain protein; KEGG: swi:Swit_2332 heat shock protein DnaJ domain-containing protein. | TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; Torsin; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; ATP-dependent Clp protease ATP-binding subunit clpA; KEGG: swi:Swit_0126 ATP-dependent Clp protease, ATP-binding subunit ClpA; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | 0.607 |
ZMO1545 | clpB | ZMO1545 | ZMO1424 | PFAM: heat shock protein DnaJ domain protein; KEGG: swi:Swit_2332 heat shock protein DnaJ domain-containing protein. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.607 |
ZMO1545 | dnaK | ZMO1545 | ZMO0660 | PFAM: heat shock protein DnaJ domain protein; KEGG: swi:Swit_2332 heat shock protein DnaJ domain-containing protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.957 |
ZMO1545 | groL | ZMO1545 | ZMO1929 | PFAM: heat shock protein DnaJ domain protein; KEGG: swi:Swit_2332 heat shock protein DnaJ domain-containing protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.577 |