STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hpnDSqualene synthase HpnD; Involved in the biosynthesis of the hopanoid precursor squalene (SQ) from farnesyl diphosphate (FPP). Catalyzes the first step, the formation of presqualene diphosphate (PSPP) from two molecules of FPP. (291 aa)    
Predicted Functional Partners:
hpnE
Squalene-associated FAD-dependent desaturase; Involved in the biosynthesis of the hopanoid precursor squalene (SQ) from farnesyl diphosphate (FPP). Catalyzes the third (last) step, the reduction of hydroxysqualene (HSQ) to SQ.
   
 0.997
hpnC
Squalene synthase HpnC; Involved in the biosynthesis of the hopanoid precursor squalene (SQ) from farnesyl diphosphate (FPP). Catalyzes the second step, the conversion of presqualene diphosphate (PSPP) to hydroxysqualene (HSQ).
  
0.994
ZMO0868
KEGG: bph:Bphy_4129 hopene-associated glycosyltransferase HpnB; TIGRFAM: hopene-associated glycosyltransferase HpnB; PFAM: glycosyl transferase family 2.
  
 0.992
shc
Squalene-hopene cyclase; Catalyzes the cyclization of squalene into hopene.
 
  
 0.957
ZMO0867
KEGG: bmu:Bmul_3257 hopanoid-associated sugar epimerase; TIGRFAM: hopanoid-associated sugar epimerase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain.
 
 
 0.925
ZMO1399
PFAM: fatty acid hydroxylase; KEGG: swi:Swit_3907 fatty acid hydroxylase.
  
 
 0.776
ZMO0873
Hopanoid-associated phosphorylase; KEGG: bid:Bind_3157 hypothetical protein; TIGRFAM: hopanoid-associated phosphorylase; PFAM: purine or other phosphorylase family 1.
 
   
 0.761
gap
Glyceraldehyde-3-phosphate dehydrogenase, type I; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
   
  
 0.697
ZMO1548
TIGRFAM: squalene/oxidosqualene cyclase; squalene-hopene cyclase; KEGG: bbt:BBta_1355 squalene-hopene cyclase; PFAM: Prenyltransferase/squalene oxidase.
 
  
 0.690
ZMO0214
MATE efflux family protein; KEGG: hch:HCH_00046 Na+-driven multidrug efflux pump; TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE.
   
   0.674
Your Current Organism:
Zymomonas mobilis ZM4
NCBI taxonomy Id: 264203
Other names: Z. mobilis subsp. mobilis ZM4 = ATCC 31821, Zymomonas mobilis subsp. mobilis ATCC 31821, Zymomonas mobilis subsp. mobilis ATCC 31821 = ZM4, Zymomonas mobilis subsp. mobilis ZM4, Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.