STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hpnESqualene-associated FAD-dependent desaturase; Involved in the biosynthesis of the hopanoid precursor squalene (SQ) from farnesyl diphosphate (FPP). Catalyzes the third (last) step, the reduction of hydroxysqualene (HSQ) to SQ. (414 aa)    
Predicted Functional Partners:
hpnD
Squalene synthase HpnD; Involved in the biosynthesis of the hopanoid precursor squalene (SQ) from farnesyl diphosphate (FPP). Catalyzes the first step, the formation of presqualene diphosphate (PSPP) from two molecules of FPP.
   
 0.997
hpnC
Squalene synthase HpnC; Involved in the biosynthesis of the hopanoid precursor squalene (SQ) from farnesyl diphosphate (FPP). Catalyzes the second step, the conversion of presqualene diphosphate (PSPP) to hydroxysqualene (HSQ).
 
   
 0.989
shc
Squalene-hopene cyclase; Catalyzes the cyclization of squalene into hopene.
 
   
 0.972
ZMO0868
KEGG: bph:Bphy_4129 hopene-associated glycosyltransferase HpnB; TIGRFAM: hopene-associated glycosyltransferase HpnB; PFAM: glycosyl transferase family 2.
 
     0.919
ZMO0867
KEGG: bmu:Bmul_3257 hopanoid-associated sugar epimerase; TIGRFAM: hopanoid-associated sugar epimerase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain.
 
  
 0.916
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
  
 0.904
ZMO1548
TIGRFAM: squalene/oxidosqualene cyclase; squalene-hopene cyclase; KEGG: bbt:BBta_1355 squalene-hopene cyclase; PFAM: Prenyltransferase/squalene oxidase.
  
   
 0.850
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
  
  
 0.842
ZMO0873
Hopanoid-associated phosphorylase; KEGG: bid:Bind_3157 hypothetical protein; TIGRFAM: hopanoid-associated phosphorylase; PFAM: purine or other phosphorylase family 1.
 
     0.790
ZMO1599
TIGRFAM: hopanoid biosynthesis associated RND transporter like protein HpnN; KEGG: bid:Bind_3159 hopanoid biosynthesis associated RND transporter like protein HpnN.
  
     0.700
Your Current Organism:
Zymomonas mobilis ZM4
NCBI taxonomy Id: 264203
Other names: Z. mobilis subsp. mobilis ZM4 = ATCC 31821, Zymomonas mobilis subsp. mobilis ATCC 31821, Zymomonas mobilis subsp. mobilis ATCC 31821 = ZM4, Zymomonas mobilis subsp. mobilis ZM4, Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821
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