STRINGSTRING
eda protein (Zymomonas mobilis ZM4) - STRING interaction network
"eda" - KHG/KDPG aldolase in Zymomonas mobilis ZM4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
edaKHG/KDPG aldolase; KEGG- mex-Mext_2006 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; TIGRFAM- 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM- KDPG and KHG aldolase; Belongs to the KHG/KDPG aldolase family (208 aa)    
Predicted Functional Partners:
edd
Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family (607 aa)
 
  0.995
gap
Glyceraldehyde-3-phosphate dehydrogenase; Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG (337 aa)
   
 
  0.949
glk
TIGRFAM- glucokinase; KEGG- gdj-Gdia_3540 glucokinase; PFAM- Glucokinase; Belongs to the bacterial glucokinase family (324 aa)
 
 
  0.945
ZMO1883
PFAM- D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG- mmw-Mmwyl1_3293 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding (313 aa)
 
   
    0.917
pgi
Glucose-6-phosphate isomerase; Provides a gateway for fructose into the Entner- Doudouroff pathway; Belongs to the GPI family (507 aa)
     
  0.895
ZMO0152
TIGRFAM- pyruvate kinase; KEGG- swi-Swit_3121 pyruvate kinase; PFAM- Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family (475 aa)
   
 
  0.887
ZMO0996
PFAM- MscS Mechanosensitive ion channel; KEGG- mpo-Mpop_3940 MscS mechanosensitive ion channel (380 aa)
              0.845
eno
Enolase; Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family (429 aa)
         
  0.844
ZMO0179
KEGG- rce-RC1_1822 fructose-bisphosphate aldolase; PFAM- deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase (304 aa)
         
  0.842
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family (249 aa)
         
  0.839
Your Current Organism:
Zymomonas mobilis ZM4
NCBI taxonomy Id: 264203
Other names: Z. mobilis subsp. mobilis ZM4 = ATCC 31821, Zymomonas mobilis ZM4, Zymomonas mobilis subsp. mobilis ATCC 31821, Zymomonas mobilis subsp. mobilis ATCC 31821 = ZM4, Zymomonas mobilis subsp. mobilis ZM4, Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821
Server load: low (6%) [ZH]