| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ZMO0059 | ZMO1689 | ZMO0059 | ZMO1689 | KEGG: lbr:LVIS_0413 glycerate kinase; PFAM: glycerate kinase; Belongs to the glycerate kinase type-1 family. | TIGRFAM: dihydroorotase, multifunctional complex type; KEGG: swi:Swit_2737 dihydroorotase; PFAM: amidohydrolase. | 0.881 |
| ZMO0120 | ZMO0587 | ZMO0120 | ZMO0587 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). | 0.974 |
| ZMO0120 | ZMO0792 | ZMO0120 | ZMO0792 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | Dihydroorotase; KEGG: swi:Swit_0603 dihydroorotase; PFAM: amidohydrolase. | 0.981 |
| ZMO0120 | ZMO1689 | ZMO0120 | ZMO1689 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | TIGRFAM: dihydroorotase, multifunctional complex type; KEGG: swi:Swit_2737 dihydroorotase; PFAM: amidohydrolase. | 0.983 |
| ZMO0120 | carA | ZMO0120 | ZMO1618 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | KEGG: swi:Swit_0435 carbamoyl phosphate synthase small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | 0.955 |
| ZMO0120 | guaA | ZMO0120 | ZMO1267 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.623 |
| ZMO0120 | guaB | ZMO0120 | ZMO1321 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.553 |
| ZMO0120 | pyrB | ZMO0120 | ZMO0791 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | KEGG: swi:Swit_0602 aspartate carbamoyltransferase catalytic subunit; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.974 |
| ZMO0120 | pyrE | ZMO0120 | ZMO1707 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.997 |
| ZMO0587 | ZMO0120 | ZMO0587 | ZMO0120 | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | 0.974 |
| ZMO0587 | ZMO0792 | ZMO0587 | ZMO0792 | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). | Dihydroorotase; KEGG: swi:Swit_0603 dihydroorotase; PFAM: amidohydrolase. | 0.822 |
| ZMO0587 | ZMO1689 | ZMO0587 | ZMO1689 | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). | TIGRFAM: dihydroorotase, multifunctional complex type; KEGG: swi:Swit_2737 dihydroorotase; PFAM: amidohydrolase. | 0.792 |
| ZMO0587 | carA | ZMO0587 | ZMO1618 | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). | KEGG: swi:Swit_0435 carbamoyl phosphate synthase small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | 0.965 |
| ZMO0587 | guaA | ZMO0587 | ZMO1267 | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.571 |
| ZMO0587 | guaB | ZMO0587 | ZMO1321 | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.572 |
| ZMO0587 | pyrB | ZMO0587 | ZMO0791 | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). | KEGG: swi:Swit_0602 aspartate carbamoyltransferase catalytic subunit; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.981 |
| ZMO0587 | pyrE | ZMO0587 | ZMO1707 | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.997 |
| ZMO0792 | ZMO0120 | ZMO0792 | ZMO0120 | Dihydroorotase; KEGG: swi:Swit_0603 dihydroorotase; PFAM: amidohydrolase. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | 0.981 |
| ZMO0792 | ZMO0587 | ZMO0792 | ZMO0587 | Dihydroorotase; KEGG: swi:Swit_0603 dihydroorotase; PFAM: amidohydrolase. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). | 0.822 |
| ZMO0792 | ZMO1689 | ZMO0792 | ZMO1689 | Dihydroorotase; KEGG: swi:Swit_0603 dihydroorotase; PFAM: amidohydrolase. | TIGRFAM: dihydroorotase, multifunctional complex type; KEGG: swi:Swit_2737 dihydroorotase; PFAM: amidohydrolase. | 0.927 |