| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ZMO1978 | ZMO1979 | ZMO1978 | ZMO1979 | parB-like partition protein; KEGG: swi:Swit_2849 chromosome segregation DNA-binding protein; TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; Belongs to the ParB family. | PFAM: Cobyrinic acid ac-diamide synthase; KEGG: sal:Sala_2856 cobyrinic acid a,c-diamide synthase. | 0.999 |
| ZMO1978 | mnmE | ZMO1978 | ZMO1988 | parB-like partition protein; KEGG: swi:Swit_2849 chromosome segregation DNA-binding protein; TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; Belongs to the ParB family. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.628 |
| ZMO1978 | mnmG | ZMO1978 | ZMO1981 | parB-like partition protein; KEGG: swi:Swit_2849 chromosome segregation DNA-binding protein; TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; Belongs to the ParB family. | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.852 |
| ZMO1978 | polA | ZMO1978 | ZMO0227 | parB-like partition protein; KEGG: swi:Swit_2849 chromosome segregation DNA-binding protein; TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; Belongs to the ParB family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.423 |
| ZMO1978 | rsmG | ZMO1978 | ZMO1980 | parB-like partition protein; KEGG: swi:Swit_2849 chromosome segregation DNA-binding protein; TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; Belongs to the ParB family. | Methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.953 |
| ZMO1979 | ZMO1978 | ZMO1979 | ZMO1978 | PFAM: Cobyrinic acid ac-diamide synthase; KEGG: sal:Sala_2856 cobyrinic acid a,c-diamide synthase. | parB-like partition protein; KEGG: swi:Swit_2849 chromosome segregation DNA-binding protein; TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; Belongs to the ParB family. | 0.999 |
| ZMO1979 | mnmG | ZMO1979 | ZMO1981 | PFAM: Cobyrinic acid ac-diamide synthase; KEGG: sal:Sala_2856 cobyrinic acid a,c-diamide synthase. | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.831 |
| ZMO1979 | rsmG | ZMO1979 | ZMO1980 | PFAM: Cobyrinic acid ac-diamide synthase; KEGG: sal:Sala_2856 cobyrinic acid a,c-diamide synthase. | Methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.864 |
| ftsY | guaB | ZMO1070 | ZMO1321 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.499 |
| ftsY | polA | ZMO1070 | ZMO0227 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.595 |
| ftsY | rsmG | ZMO1070 | ZMO1980 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | Methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.527 |
| ftsY | yidC | ZMO1070 | ZMO1626 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | YidC translocase/secretase; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.936 |
| guaB | ftsY | ZMO1321 | ZMO1070 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | 0.499 |
| guaB | mnmG | ZMO1321 | ZMO1981 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.465 |
| guaB | polA | ZMO1321 | ZMO0227 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.522 |
| guaB | rpsL | ZMO1321 | ZMO2002 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. | 0.468 |
| guaB | rsmG | ZMO1321 | ZMO1980 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.554 |
| guaB | yidC | ZMO1321 | ZMO1626 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | YidC translocase/secretase; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.529 |
| mnmE | ZMO1978 | ZMO1988 | ZMO1978 | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | parB-like partition protein; KEGG: swi:Swit_2849 chromosome segregation DNA-binding protein; TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; Belongs to the ParB family. | 0.628 |
| mnmE | mnmG | ZMO1988 | ZMO1981 | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.997 |