STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kynATryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (289 aa)    
Predicted Functional Partners:
kynU
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.
 
 
 0.997
FB00_02360
Regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.866
FB00_02350
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.829
FB00_17055
Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.800
FB00_10590
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.744
FB00_01065
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.666
FB00_19455
Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.666
FB00_02340
Histidine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate mutase family.
       0.598
FB00_16990
Septum formation inhibitor Maf; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
    
   0.571
FB00_02170
Pyridoxal-dependent decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.533
Your Current Organism:
Cellulosimicrobium funkei
NCBI taxonomy Id: 264251
Other names: ATCC BAA-886, C. funkei, CCUG 50705, Cellulosimicrobium funkei Brown et al. 2006, Cellulosimicrobium sp. AR6, Cellulosimicrobium sp. AR8, DSM 16025, JCM 14302, NBRC 104118, NCTC 13516, strain W6122
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