STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FB00_02750Converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (445 aa)    
Predicted Functional Partners:
FB00_10580
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.999
gltD
Glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.980
FB00_16525
Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.978
FB00_16560
Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family.
  
 
 0.974
FB00_05595
Nitrite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
   
 
 0.969
argJ
N-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
     
 0.969
FB00_06635
Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family.
  
 
 0.904
FB00_14260
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family.
   
 0.904
FB00_09175
Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.893
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
   
 
 0.877
Your Current Organism:
Cellulosimicrobium funkei
NCBI taxonomy Id: 264251
Other names: ATCC BAA-886, C. funkei, CCUG 50705, Cellulosimicrobium funkei Brown et al. 2006, Cellulosimicrobium sp. AR6, Cellulosimicrobium sp. AR8, DSM 16025, JCM 14302, NBRC 104118, NCTC 13516, strain W6122
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