STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acsAacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (672 aa)    
Predicted Functional Partners:
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
 
 0.988
FB00_14260
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family.
  
 0.988
FB00_17425
Acetaldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 0.984
FB00_11770
Phosphate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.981
FB00_08015
acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.976
FB00_10100
acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.976
FB00_10035
Catalyzes the oxidation of acetaldehyde, benzaldehyde, propionaldehyde and other aldehydes; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.975
FB00_08960
Transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.971
FB00_17020
methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.970
FB00_16985
acetyl-COA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.969
Your Current Organism:
Cellulosimicrobium funkei
NCBI taxonomy Id: 264251
Other names: ATCC BAA-886, C. funkei, CCUG 50705, Cellulosimicrobium funkei Brown et al. 2006, Cellulosimicrobium sp. AR6, Cellulosimicrobium sp. AR8, DSM 16025, JCM 14302, NBRC 104118, NCTC 13516, strain W6122
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