STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaE2DNA polymerase III subunit alpha; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1212 aa)    
Predicted Functional Partners:
FB00_18360
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.969
FB00_11325
DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.954
FB00_00520
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 0.947
FB00_12030
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.925
FB00_07755
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.914
FB00_03405
DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.885
FB00_12025
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.868
FB00_00655
Single-stranded DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.866
FB00_12420
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.837
FB00_20775
Endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.826
Your Current Organism:
Cellulosimicrobium funkei
NCBI taxonomy Id: 264251
Other names: ATCC BAA-886, C. funkei, CCUG 50705, Cellulosimicrobium funkei Brown et al. 2006, Cellulosimicrobium sp. AR6, Cellulosimicrobium sp. AR8, DSM 16025, JCM 14302, NBRC 104118, NCTC 13516, strain W6122
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.