STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bd1620acetyl-CoA hydrolase/transferase family protein; Region start changed from 1552387 to 1552363 (-24 bases). (495 aa)    
Predicted Functional Partners:
Bd0504
acetyl-CoA synthetase; AMP-binding protein; hypothetical protein.
  
 0.944
acs
Acetyl coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.944
icmF
methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
  
  
 0.920
atoB
AtoB protein; InterPro: Thiolase, mitochondrial 3-oxoacyl-Coenzyme A thiolase; hypothetical protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.917
pdhC
Pyruvate dehydrogenase E2; InterPro: 2-Oxo acid dehydrogenase acyltransferase catalytic domain, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes; hypothetical protein.
   
 0.917
Bd2070
acetyl-CoA acyltransferase; InterPro: Thiolase; hypothetical protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.917
Bd2095
Probable acetyl-CoA acetyltransferase; InterPro: Thiolase; hypothetical protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.917
aldH
InterPro: Aldehyde dehydrogenase family; hypothetical protein.
  
 
 0.911
sucC
succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 0.892
sucD
succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
 0.885
Your Current Organism:
Bdellovibrio bacteriovorus HD100
NCBI taxonomy Id: 264462
Other names: B. bacteriovorus HD100, Bdellovibrio bacteriovorus DSM 50701, Bdellovibrio bacteriovorus str. HD100, Bdellovibrio bacteriovorus strain HD100
Server load: low (24%) [HD]
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