STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
citInterPro: Citrate synthase; hypothetical protein. (388 aa)    
Predicted Functional Partners:
Bd2500
2-methylcitrate dehydratase.
 
 
 0.988
Bd0504
acetyl-CoA synthetase; AMP-binding protein; hypothetical protein.
  
 0.970
acs
Acetyl coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.970
Bd1836
InterPro: 3-hydroxyacyl-CoA dehydrogenase, fatty oxidation complex, alpha subunit [EC:1.1.1.35 4.2.1.17 5.1.2.3]; hypothetical protein; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.963
Bd2502
2-methylisocitratelyase 2; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
 
 0.954
mmsA
Methylmalonate-semialdehyde dehydrogenase.
  
 0.943
pccB
propionyl-CoA carboxylase beta chain.
  
 
 0.937
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.928
acnA
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
 
 0.925
leuC
3-isopropylmalate isomerase; InterPro: Aconitate hydratase N-terminal; hypothetical protein.
 
 0.915
Your Current Organism:
Bdellovibrio bacteriovorus HD100
NCBI taxonomy Id: 264462
Other names: B. bacteriovorus HD100, Bdellovibrio bacteriovorus DSM 50701, Bdellovibrio bacteriovorus str. HD100, Bdellovibrio bacteriovorus strain HD100
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