node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bd0200 | aroK | Bd0200 | Bd3494 | Hemolysin A, probable rRNA methylase; hypothetical protein. | Shikimate synthase; Probable pentafunctional arom polypeptide (EC 2.5.1.19)(3-phosphoshikimate 1-carboxyvinyltransferase) (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS); hypothetical protein. | 0.424 |
Bd0200 | ppnK | Bd0200 | Bd3172 | Hemolysin A, probable rRNA methylase; hypothetical protein. | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.677 |
Bd3174 | dcp | Bd3174 | Bd3171 | Putative nucleoside-diphosphate-sugar epimerase. | Peptidyl-dipeptidase. | 0.494 |
Bd3174 | ppnK | Bd3174 | Bd3172 | Putative nucleoside-diphosphate-sugar epimerase. | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.558 |
Bd3174 | recN | Bd3174 | Bd3173 | Putative nucleoside-diphosphate-sugar epimerase. | DNA repair protein; May be involved in recombinational repair of damaged DNA. | 0.517 |
aroK | Bd0200 | Bd3494 | Bd0200 | Shikimate synthase; Probable pentafunctional arom polypeptide (EC 2.5.1.19)(3-phosphoshikimate 1-carboxyvinyltransferase) (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS); hypothetical protein. | Hemolysin A, probable rRNA methylase; hypothetical protein. | 0.424 |
aroK | nadE | Bd3494 | Bd3836 | Shikimate synthase; Probable pentafunctional arom polypeptide (EC 2.5.1.19)(3-phosphoshikimate 1-carboxyvinyltransferase) (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS); hypothetical protein. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.594 |
aroK | ppnK | Bd3494 | Bd3172 | Shikimate synthase; Probable pentafunctional arom polypeptide (EC 2.5.1.19)(3-phosphoshikimate 1-carboxyvinyltransferase) (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS); hypothetical protein. | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.729 |
aroK | ribA | Bd3494 | Bd3038 | Shikimate synthase; Probable pentafunctional arom polypeptide (EC 2.5.1.19)(3-phosphoshikimate 1-carboxyvinyltransferase) (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS); hypothetical protein. | GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.548 |
aroK | rsfS | Bd3494 | Bd3846 | Shikimate synthase; Probable pentafunctional arom polypeptide (EC 2.5.1.19)(3-phosphoshikimate 1-carboxyvinyltransferase) (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS); hypothetical protein. | Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). Belongs to the Iojap/RsfS family. | 0.979 |
cobB | nadE | Bd2785 | Bd3836 | Putative nicotinic acid mononucleotide:5,6-dimethylbenzimidazole (DMB) phosphoribosyltransferase; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.967 |
cobB | ppnK | Bd2785 | Bd3172 | Putative nicotinic acid mononucleotide:5,6-dimethylbenzimidazole (DMB) phosphoribosyltransferase; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.926 |
cobB | rsfS | Bd2785 | Bd3846 | Putative nicotinic acid mononucleotide:5,6-dimethylbenzimidazole (DMB) phosphoribosyltransferase; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. | Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). Belongs to the Iojap/RsfS family. | 0.959 |
dcp | Bd3174 | Bd3171 | Bd3174 | Peptidyl-dipeptidase. | Putative nucleoside-diphosphate-sugar epimerase. | 0.494 |
dcp | ppnK | Bd3171 | Bd3172 | Peptidyl-dipeptidase. | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.840 |
dcp | recN | Bd3171 | Bd3173 | Peptidyl-dipeptidase. | DNA repair protein; May be involved in recombinational repair of damaged DNA. | 0.751 |
nadE | aroK | Bd3836 | Bd3494 | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | Shikimate synthase; Probable pentafunctional arom polypeptide (EC 2.5.1.19)(3-phosphoshikimate 1-carboxyvinyltransferase) (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS); hypothetical protein. | 0.594 |
nadE | cobB | Bd3836 | Bd2785 | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | Putative nicotinic acid mononucleotide:5,6-dimethylbenzimidazole (DMB) phosphoribosyltransferase; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. | 0.967 |
nadE | ppnK | Bd3836 | Bd3172 | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.973 |
nadE | ribA | Bd3836 | Bd3038 | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.761 |