node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aroK | nadE | Bd3494 | Bd3836 | Shikimate synthase; Probable pentafunctional arom polypeptide (EC 2.5.1.19)(3-phosphoshikimate 1-carboxyvinyltransferase) (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS); hypothetical protein. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.594 |
aroK | ppnK | Bd3494 | Bd3172 | Shikimate synthase; Probable pentafunctional arom polypeptide (EC 2.5.1.19)(3-phosphoshikimate 1-carboxyvinyltransferase) (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS); hypothetical protein. | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.729 |
aroK | rplU | Bd3494 | Bd3849 | Shikimate synthase; Probable pentafunctional arom polypeptide (EC 2.5.1.19)(3-phosphoshikimate 1-carboxyvinyltransferase) (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS); hypothetical protein. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.425 |
aroK | rsfS | Bd3494 | Bd3846 | Shikimate synthase; Probable pentafunctional arom polypeptide (EC 2.5.1.19)(3-phosphoshikimate 1-carboxyvinyltransferase) (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS); hypothetical protein. | Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). Belongs to the Iojap/RsfS family. | 0.979 |
che | nadC | Bd0510 | Bd2762 | CinA-like protein; CheA (cheA), CheW (cheW) and CheY (cheY) genes, competence-damage inducible protein; hypothetical protein; Belongs to the CinA family. | NadC protein; InterPro: Nicotinate-nucleotide pyrophosphorylase; hypothetical protein; Belongs to the NadC/ModD family. | 0.921 |
che | nadE | Bd0510 | Bd3836 | CinA-like protein; CheA (cheA), CheW (cheW) and CheY (cheY) genes, competence-damage inducible protein; hypothetical protein; Belongs to the CinA family. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.690 |
che | rsfS | Bd0510 | Bd3846 | CinA-like protein; CheA (cheA), CheW (cheW) and CheY (cheY) genes, competence-damage inducible protein; hypothetical protein; Belongs to the CinA family. | Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). Belongs to the Iojap/RsfS family. | 0.976 |
cobB | nadE | Bd2785 | Bd3836 | Putative nicotinic acid mononucleotide:5,6-dimethylbenzimidazole (DMB) phosphoribosyltransferase; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.967 |
cobB | ppnK | Bd2785 | Bd3172 | Putative nicotinic acid mononucleotide:5,6-dimethylbenzimidazole (DMB) phosphoribosyltransferase; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.926 |
cobB | rsfS | Bd2785 | Bd3846 | Putative nicotinic acid mononucleotide:5,6-dimethylbenzimidazole (DMB) phosphoribosyltransferase; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. | Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). Belongs to the Iojap/RsfS family. | 0.959 |
nadC | che | Bd2762 | Bd0510 | NadC protein; InterPro: Nicotinate-nucleotide pyrophosphorylase; hypothetical protein; Belongs to the NadC/ModD family. | CinA-like protein; CheA (cheA), CheW (cheW) and CheY (cheY) genes, competence-damage inducible protein; hypothetical protein; Belongs to the CinA family. | 0.921 |
nadC | nadE | Bd2762 | Bd3836 | NadC protein; InterPro: Nicotinate-nucleotide pyrophosphorylase; hypothetical protein; Belongs to the NadC/ModD family. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.715 |
nadC | rsfS | Bd2762 | Bd3846 | NadC protein; InterPro: Nicotinate-nucleotide pyrophosphorylase; hypothetical protein; Belongs to the NadC/ModD family. | Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). Belongs to the Iojap/RsfS family. | 0.963 |
nadE | aroK | Bd3836 | Bd3494 | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | Shikimate synthase; Probable pentafunctional arom polypeptide (EC 2.5.1.19)(3-phosphoshikimate 1-carboxyvinyltransferase) (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS); hypothetical protein. | 0.594 |
nadE | che | Bd3836 | Bd0510 | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | CinA-like protein; CheA (cheA), CheW (cheW) and CheY (cheY) genes, competence-damage inducible protein; hypothetical protein; Belongs to the CinA family. | 0.690 |
nadE | cobB | Bd3836 | Bd2785 | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | Putative nicotinic acid mononucleotide:5,6-dimethylbenzimidazole (DMB) phosphoribosyltransferase; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. | 0.967 |
nadE | nadC | Bd3836 | Bd2762 | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | NadC protein; InterPro: Nicotinate-nucleotide pyrophosphorylase; hypothetical protein; Belongs to the NadC/ModD family. | 0.715 |
nadE | ppnK | Bd3836 | Bd3172 | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.973 |
nadE | rsfS | Bd3836 | Bd3846 | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). Belongs to the Iojap/RsfS family. | 0.975 |
obg | rlmH | Bd3847 | Bd3845 | GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.824 |