node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PRU_0033 | PRU_0034 | PRU_0033 | PRU_0034 | Peptidylprolyl isomerase domain protein; Identified by match to protein family HMM PF00639. | Peptidylprolyl isomerase domain protein; Identified by match to protein family HMM PF00639; match to protein family HMM PF09312. | 0.937 |
PRU_0033 | PRU_0035 | PRU_0033 | PRU_0035 | Peptidylprolyl isomerase domain protein; Identified by match to protein family HMM PF00639. | Conserved hypothetical protein; Identified by similarity to GB:AAQ65615.1. | 0.777 |
PRU_0033 | clpP | PRU_0033 | PRU_0029 | Peptidylprolyl isomerase domain protein; Identified by match to protein family HMM PF00639. | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.716 |
PRU_0033 | clpX | PRU_0033 | PRU_0030 | Peptidylprolyl isomerase domain protein; Identified by match to protein family HMM PF00639. | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.656 |
PRU_0033 | guaB | PRU_0033 | PRU_0032 | Peptidylprolyl isomerase domain protein; Identified by match to protein family HMM PF00639. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.884 |
PRU_0033 | mutL | PRU_0033 | PRU_0036 | Peptidylprolyl isomerase domain protein; Identified by match to protein family HMM PF00639. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.783 |
PRU_0033 | recQ_1 | PRU_0033 | PRU_0031 | Peptidylprolyl isomerase domain protein; Identified by match to protein family HMM PF00639. | ATP-dependent DNA helicase RecQ; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM PF09382; match to protein family HMM TIGR00614; match to protein family HMM TIGR01389. | 0.697 |
PRU_0033 | tig | PRU_0033 | PRU_0028 | Peptidylprolyl isomerase domain protein; Identified by match to protein family HMM PF00639. | Trigger factor; Identified by similarity to SP:P22257; match to protein family HMM PF05697; match to protein family HMM TIGR00115. | 0.612 |
PRU_0034 | PRU_0033 | PRU_0034 | PRU_0033 | Peptidylprolyl isomerase domain protein; Identified by match to protein family HMM PF00639; match to protein family HMM PF09312. | Peptidylprolyl isomerase domain protein; Identified by match to protein family HMM PF00639. | 0.937 |
PRU_0034 | PRU_0035 | PRU_0034 | PRU_0035 | Peptidylprolyl isomerase domain protein; Identified by match to protein family HMM PF00639; match to protein family HMM PF09312. | Conserved hypothetical protein; Identified by similarity to GB:AAQ65615.1. | 0.886 |
PRU_0034 | clpP | PRU_0034 | PRU_0029 | Peptidylprolyl isomerase domain protein; Identified by match to protein family HMM PF00639; match to protein family HMM PF09312. | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.693 |
PRU_0034 | clpX | PRU_0034 | PRU_0030 | Peptidylprolyl isomerase domain protein; Identified by match to protein family HMM PF00639; match to protein family HMM PF09312. | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.628 |
PRU_0034 | guaB | PRU_0034 | PRU_0032 | Peptidylprolyl isomerase domain protein; Identified by match to protein family HMM PF00639; match to protein family HMM PF09312. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.860 |
PRU_0034 | mutL | PRU_0034 | PRU_0036 | Peptidylprolyl isomerase domain protein; Identified by match to protein family HMM PF00639; match to protein family HMM PF09312. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.807 |
PRU_0034 | recQ_1 | PRU_0034 | PRU_0031 | Peptidylprolyl isomerase domain protein; Identified by match to protein family HMM PF00639; match to protein family HMM PF09312. | ATP-dependent DNA helicase RecQ; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM PF09382; match to protein family HMM TIGR00614; match to protein family HMM TIGR01389. | 0.666 |
PRU_0034 | tig | PRU_0034 | PRU_0028 | Peptidylprolyl isomerase domain protein; Identified by match to protein family HMM PF00639; match to protein family HMM PF09312. | Trigger factor; Identified by similarity to SP:P22257; match to protein family HMM PF05697; match to protein family HMM TIGR00115. | 0.696 |
PRU_0035 | PRU_0033 | PRU_0035 | PRU_0033 | Conserved hypothetical protein; Identified by similarity to GB:AAQ65615.1. | Peptidylprolyl isomerase domain protein; Identified by match to protein family HMM PF00639. | 0.777 |
PRU_0035 | PRU_0034 | PRU_0035 | PRU_0034 | Conserved hypothetical protein; Identified by similarity to GB:AAQ65615.1. | Peptidylprolyl isomerase domain protein; Identified by match to protein family HMM PF00639; match to protein family HMM PF09312. | 0.886 |
PRU_0035 | clpP | PRU_0035 | PRU_0029 | Conserved hypothetical protein; Identified by similarity to GB:AAQ65615.1. | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.528 |
PRU_0035 | clpX | PRU_0035 | PRU_0030 | Conserved hypothetical protein; Identified by similarity to GB:AAQ65615.1. | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.528 |