STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRU_0331RNA polymerase sigma-70 factor family protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (240 aa)    
Predicted Functional Partners:
PRU_2699
Sensor histidine kinase/DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00165; match to protein family HMM PF00512; match to protein family HMM PF02518; match to protein family HMM PF07494; match to protein family HMM PF07495.
   
 
 0.655
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.561
PRU_0332
RyR domain protein; Identified by match to protein family HMM PF02026.
     
 0.522
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.511
PRU_0330
Hypothetical protein; Identified by glimmer; putative.
       0.510
PRU_0333
Hypothetical protein; Identified by glimmer; putative.
       0.509
PRU_0334
Hypothetical protein; Identified by glimmer; putative.
       0.509
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.504
PRU_0329
Hypothetical protein; Identified by glimmer; putative.
       0.491
PRU_1354
Conserved hypothetical protein; Identified by similarity to GB:AAQ66307.1.
   
 
 0.480
Your Current Organism:
Prevotella ruminicola
NCBI taxonomy Id: 264731
Other names: P. ruminicola 23, Prevotella ruminicola 23, Prevotella ruminicola Bryant 23, Prevotella ruminicola str. 23, Prevotella ruminicola strain 23
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.