node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PRU_0426 | PRU_0625 | PRU_0426 | PRU_0625 | Sugar transporter, fucose:hydrogen symporter (FHS) family; Identified by similarity to SP:Q44623. | Transporter, outer membrane receptor (OMR) family; Identified by match to protein family HMM PF00593; match to protein family HMM PF07715. | 0.519 |
PRU_0426 | PRU_0810 | PRU_0426 | PRU_0810 | Sugar transporter, fucose:hydrogen symporter (FHS) family; Identified by similarity to SP:Q44623. | Conserved hypothetical protein; Identified by similarity to GB:AAQ66361.1. | 0.480 |
PRU_0426 | PRU_2277 | PRU_0426 | PRU_2277 | Sugar transporter, fucose:hydrogen symporter (FHS) family; Identified by similarity to SP:Q44623. | Sugar transporter, fucose:hydrogen symporter (FHS) family; Identified by similarity to SP:Q44623; match to protein family HMM PF07690. | 0.443 |
PRU_0426 | dnaJ | PRU_0426 | PRU_0429 | Sugar transporter, fucose:hydrogen symporter (FHS) family; Identified by similarity to SP:Q44623. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.467 |
PRU_0426 | folC | PRU_0426 | PRU_0428 | Sugar transporter, fucose:hydrogen symporter (FHS) family; Identified by similarity to SP:Q44623. | Tetrahydrofolate synthase; Identified by similarity to SP:Q05865; match to protein family HMM PF08245; match to protein family HMM TIGR01499; Belongs to the folylpolyglutamate synthase family. | 0.495 |
PRU_0426 | fucP | PRU_0426 | PRU_2839 | Sugar transporter, fucose:hydrogen symporter (FHS) family; Identified by similarity to SP:Q44623. | L-fucose permease; Identified by similarity to SP:P11551; match to protein family HMM PF07690; match to protein family HMM TIGR00885. | 0.543 |
PRU_0426 | galK | PRU_0426 | PRU_0425 | Sugar transporter, fucose:hydrogen symporter (FHS) family; Identified by similarity to SP:Q44623. | Galactokinase; Identified by similarity to SP:P39574; match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR00131; Belongs to the GHMP kinase family. GalK subfamily. | 0.813 |
PRU_0426 | galM_1 | PRU_0426 | PRU_0424 | Sugar transporter, fucose:hydrogen symporter (FHS) family; Identified by similarity to SP:Q44623. | Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. | 0.471 |
PRU_0426 | galM_2 | PRU_0426 | PRU_0427 | Sugar transporter, fucose:hydrogen symporter (FHS) family; Identified by similarity to SP:Q44623. | Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. | 0.781 |
PRU_0426 | grpE | PRU_0426 | PRU_0430 | Sugar transporter, fucose:hydrogen symporter (FHS) family; Identified by similarity to SP:Q44623. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.441 |
PRU_0625 | PRU_0426 | PRU_0625 | PRU_0426 | Transporter, outer membrane receptor (OMR) family; Identified by match to protein family HMM PF00593; match to protein family HMM PF07715. | Sugar transporter, fucose:hydrogen symporter (FHS) family; Identified by similarity to SP:Q44623. | 0.519 |
PRU_0625 | PRU_0810 | PRU_0625 | PRU_0810 | Transporter, outer membrane receptor (OMR) family; Identified by match to protein family HMM PF00593; match to protein family HMM PF07715. | Conserved hypothetical protein; Identified by similarity to GB:AAQ66361.1. | 0.453 |
PRU_0810 | PRU_0426 | PRU_0810 | PRU_0426 | Conserved hypothetical protein; Identified by similarity to GB:AAQ66361.1. | Sugar transporter, fucose:hydrogen symporter (FHS) family; Identified by similarity to SP:Q44623. | 0.480 |
PRU_0810 | PRU_0625 | PRU_0810 | PRU_0625 | Conserved hypothetical protein; Identified by similarity to GB:AAQ66361.1. | Transporter, outer membrane receptor (OMR) family; Identified by match to protein family HMM PF00593; match to protein family HMM PF07715. | 0.453 |
PRU_2277 | PRU_0426 | PRU_2277 | PRU_0426 | Sugar transporter, fucose:hydrogen symporter (FHS) family; Identified by similarity to SP:Q44623; match to protein family HMM PF07690. | Sugar transporter, fucose:hydrogen symporter (FHS) family; Identified by similarity to SP:Q44623. | 0.443 |
dnaJ | PRU_0426 | PRU_0429 | PRU_0426 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Sugar transporter, fucose:hydrogen symporter (FHS) family; Identified by similarity to SP:Q44623. | 0.467 |
dnaJ | folC | PRU_0429 | PRU_0428 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Tetrahydrofolate synthase; Identified by similarity to SP:Q05865; match to protein family HMM PF08245; match to protein family HMM TIGR01499; Belongs to the folylpolyglutamate synthase family. | 0.850 |
dnaJ | galK | PRU_0429 | PRU_0425 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Galactokinase; Identified by similarity to SP:P39574; match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR00131; Belongs to the GHMP kinase family. GalK subfamily. | 0.605 |
dnaJ | galM_2 | PRU_0429 | PRU_0427 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. | 0.687 |
dnaJ | grpE | PRU_0429 | PRU_0430 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.982 |