STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRU_0481ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (227 aa)    
Predicted Functional Partners:
ftsX
Cell division protein FtsX; Identified by similarity to GB:AAD50460.1; match to protein family HMM PF02687; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
 
 
 0.993
PRU_2059
ABC transporter, permease protein; Identified by match to protein family HMM PF02687.
    
 0.889
hisIE
phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase; Identified by similarity to SP:P06989; match to protein family HMM PF01502; match to protein family HMM PF01503; match to protein family HMM TIGR03188; In the N-terminal section; belongs to the PRA-CH family.
       0.787
PRU_2919
Putative tolA protein; Identified by match to protein family HMM PF01551; match to protein family HMM PF06519.
 
 
 
 0.746
hisH
Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
     
 0.718
hisF
Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
       0.704
hisA
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Identified by match to protein family HMM PF00977; match to protein family HMM TIGR00007.
       0.704
purU
Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
     
 0.691
PRU_1509
ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.
 
     0.684
lysC
Aspartate kinase; Identified by similarity to SP:P08660; match to protein family HMM PF00696; match to protein family HMM TIGR00657; Belongs to the aspartokinase family.
       0.683
Your Current Organism:
Prevotella ruminicola
NCBI taxonomy Id: 264731
Other names: P. ruminicola 23, Prevotella ruminicola 23, Prevotella ruminicola Bryant 23, Prevotella ruminicola str. 23, Prevotella ruminicola strain 23
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