STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hprAGlycerate dehydrogenase (NADH-dependent); Identified by similarity to SP:Q59516; match to protein family HMM PF00389; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (299 aa)    
Predicted Functional Partners:
PRU_1696
Identified by match to protein family HMM PF02595; match to protein family HMM TIGR00045; Belongs to the glycerate kinase type-1 family.
 
  
 0.935
PRU_0872
Putative 4-hydroxy-2-oxoglutarate aldolase/2-deydro-3-deoxyphosphogluconate aldolase; Identified by similarity to SP:P10177; match to protein family HMM PF01081.
    
 0.909
PRU_0373
Haloacid dehalogenase-like hydrolase domain protein; Identified by match to protein family HMM PF00702.
    
  0.903
PRU_1370
HAD-superfamily hydrolase, subfamily IA, variant 3; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549.
    
  0.903
PRU_1636
Amino acid ABC transporter, ATP-binding protein/permease protein, His/Glu/Gln/Arg/opine family; Identified by match to protein family HMM PF00005; match to protein family HMM PF00528; match to protein family HMM TIGR01726.
 
  
 0.570
PRU_0688
Hypothetical protein; Identified by glimmer; putative.
       0.536
nnrE
Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repa [...]
  
   0.464
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.458
PRU_2158
Putative malate dehydrogenase; Identified by similarity to SP:P10584; match to protein family HMM PF00056; match to protein family HMM PF02866; Belongs to the LDH/MDH superfamily.
  
 
 0.452
pyk
Pyruvate kinase; Identified by similarity to SP:P14178; match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family.
  
 
 0.441
Your Current Organism:
Prevotella ruminicola
NCBI taxonomy Id: 264731
Other names: P. ruminicola 23, Prevotella ruminicola 23, Prevotella ruminicola Bryant 23, Prevotella ruminicola str. 23, Prevotella ruminicola strain 23
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.