Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRU_0975Identified by match to protein family HMM PF02880. (303 aa)    
Predicted Functional Partners:
PRU_0433
Putative mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by match to protein family HMM PF00483.
  
 
 0.917
PRU_1376
Putative mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by match to protein family HMM PF00483.
  
 
 0.917
PRU_1770
Putative mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by match to protein family HMM PF00483.
  
 
 0.917
PRU_2758
Putative mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by match to protein family HMM PF00483.
  
 
 0.917
manA
Mannose-6-phosphate isomerase, class I; Identified by similarity to SP:P39841; match to protein family HMM PF01238; match to protein family HMM TIGR00218.
  
 
 0.913
PRU_0304
Identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880.
  
  
 
0.903
PRU_0974
Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165.
       0.642
PRU_0434
Glucose-1-phosphate cytidylyltransferase; Identified by similarity to GB:AAA27631.1; match to protein family HMM TIGR02623.
  
 
 0.617
dacA
Conserved hypothetical protein TIGR00159; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
   
 
 0.584
PRU_2363
Putative mannose-6-phosphate isomerase.
  
 
 0.565
Your Current Organism:
Prevotella ruminicola
NCBI taxonomy Id: 264731
Other names: P. ruminicola 23, Prevotella ruminicola 23, Prevotella ruminicola Bryant 23, Prevotella ruminicola str. 23, Prevotella ruminicola strain 23
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